Endocrine Abstracts

IntoductionThe link between hyperthyroidism and breast cancer has been the subject of much controversy and literature in the past. It poses a daily clinical problem of information and senological follow-up of thyroid patients. We report our patient’s case.ObservationA 46-year-old female patient who presented a Graves’ disease diagnosed 10 years ago. She had a moderate vascular goiter and no ocular s...

IntroductionCardiothyreosis is associated with higher morbidity and mortality than other forms of hyperthyroidism. The aim of our study was to identify its therapeutic and evolutive aspects in an adult population of southern Tunisia.MethodsRetrospective study including all cases of cardiothyreosis followed in our department during a period of 20 years.Results100 c...

Introduction: Lymphangioma is a rare benign malformation of the lymphatic system that typically affects the neck and head during childhood. Adrenal glands are an uncommon and rare location for lymphangioma. Herein, we report an unusual clinical presentation of an adrenal lymphangioma revealed by Cushing syndrome.Case report: A 69-year-old female was referred to our department for exploration of an adrenal incidentaloma. Her medical history was positive f...

Introduction: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting adrenal steroid synthesis. Its treatment aims to achieve a balance between optimal glucocorticoid replacement and normal androgen levels. The long-term outcomes of this condition are poorly studied. The objective of this study is to evaluate the impact of CAH due to 21-hydroxylase deficiency on final height (FH), bone metabolism, and cardiometabolic risk in a Tunisian cohort.<p ...

Introduction: Congenital hyperinsulinism (CHI) is a rare disease with an incidence of 1 in 30,000. It is the most common cause of persistent neonatal hypoglycemia, primarily due to inhibitory mutations in genes encoding the ATP-sensitive potassium channel in pancreatic beta cells, with ABCC8 (SUR1) and KCNJ11 (Kir6.2) mutations being the most frequent. In this context, we report a highly unusual case in terms of phenotypic and evolutionary aspects.Clinic...

Introduction: Distal and symmetrical peripheral polyneuropathy is the most frequent type of diabetic neuropathy. Its painful form (PDN) is the most common cause of non-traumatic neuropathic pain and can place a heavy burden on elderly patients’ lives. Despite the major impact that it can have on the quality of life, PDN is generally underdiagnosed because of a large interindividual variability of symptoms and in the absence of well-established diagnostic criteria.<p c...

Introduction: Mitochondrial diabetes (MD) is characterized by a wide spectrum of phenotypic and genotypic manifestations. Through a cohort study of 40 patients with MD, we attempted to establish a correlation between this diversity of phenotypic expression and the biomolecular substrate of the mitochondrial genome within the Tunisian population.Results: Epidemiologically and anthropometrically, our series aligns with literature data, with an onset age of...

Introduction: Metabolic syndrome (MS) is responsible for the increased cardiovascular risk in type 2 diabetics. There is a scarcity of research on the metabolic syndrome among individuals diagnosed with type 1 diabetes (T1DM). The aim of this study is to describe clinical, biochemical and therapeutic characteristics of T1DM with MS.Materials and Methods: Retrospective study including 36 patients, with T1DM and MS, hospitalized in the department of Endocr...

Background: Low medication adherence is a frequent problem in elderly individuals with chronic diseases such as diabetes. The objective is to assess the level of medication adherence and identify predictive factors for poor adherence among elderly diabetic patients.Methods: We conducted a descriptive, cross-sectional study among diabetic patients aged 65 years and older, who were attending the Endocrinology Department at Hedi Chaker University Hospital i...

Introduction: Diabetic foot wounds (DFW) are one of the most challenging complications of diabetes. DFW is one of the leading causes of foot ulceration and amputation in patients with diabetes mellitus. Then, a multidisciplinary approach is of a great importance in the prevention and management of DFW. Healthcare personnel, particularly nurses, have an important role in this process. The objective of our study was to evaluate nurses ‘knowledge on diabetic foot wounds mana...